The match is huge as Spurs are desperate for points in their quest to finish in the top four ahead of Chelsea, Arsenal, and Manchester United.
Harry Kane is the latest absentee and he looks set to miss the final six league games of the campaign, as well as at least one Champions League match.
His ankle injury comes at an awful time, but isn’t the only time he’s been ruled out this year having also been unavailable for eight games earlier this year.
He joins Erik Lamela (hamstring), Serge Aurier (hamstring), Eric Dier (hip flexor), and Vincent Janssen (ankle) in the treatment room ahead of their match on Saturday against the Terriers.
Meanwhile, manager Mauricio Pochettino isn’t too optimistic about Dele Alli being fit either after he broke his hand in their European victory over Manchester City on Tuesday night.
But, with all these injuries, how might Spurs look on Saturday afternoon? Find out below.