Australia have suffered a blow ahead of facing South Africa on Saturday after hooker Tatafu Polota-Nau was ruled out with a hamstring niggle.
The Wallabies hooker had been “managed” through training in Port Elizabeth this week and was initially named in the side to face the Boks but failed a fitness test on Friday.
Folau Faingaa will make his first Test start in his place, with his promotion opening up a spot for Brandon Paenga-Amosa on the bench.
The Reds hooker made his Test debut in June but this will be his first involvement in the Rugby Championship.
Australia (revised): 15 Dane Haylett-Petty, 14 Israel Folau, 13 Reece Hodge, 12 Matt Toomua, 11 Marika Koroibete, 10 Kurtley Beale, 9 Will Genia, 8 David Pocock, 7 Michael Hooper (c), 6 Ned Hanigan, 5 Izack Rodda, 4 Adam Coleman, 3 Taniela Tupou, 2 Folau Faingaa, 1 Scott Sio
Replacements: 16 Brandon Paenga-Amosa, 17 Sekope Kepu, 18 Allan Alaalatoa, 19 Rory Arnold, 20 Rob Simmons, 21 Nick Phipps, 22 Bernard Foley, 23 Jack Maddocks
Date: Saturday, September 29
Venue: Nelson Mandela Bay Stadium, Port Elizabeth
Kick-off: 17:05 local (16:05 BST, 15:05 GMT)
Referee: Jérôme Garcès (France)
Assistant referees: Wayne Barnes (England), Matthew Carley (England)
Television match official: Graham Hughes (England)