Think Dwight Yorke and Andy Cole, Alan Shearer and Chris Sutton, Frank Lampard and Didier Drogba, how about Rio Ferdinand and Nemanja Vidic?
And this season, it is Bournemouth who have the most productive duo, in the form of Callum Wilson and Ryan Fraser.
The two men played a crucial role in the 5-0 drubbing the Cherries dished out on their travels at Brighton, with Wilson setting up Fraser for their second before the diminutive attacker returned the favour for Wilson to make it four.