United have enjoyed a fine festive period, winning twice to move up to fifth in the top-flight table.
The Gunners, meanwhile, are still adjusting to life under Mikel Arteta and lost to Chelsea last time out to stay in the bottom half.
The two former title foes drew 1-1 at Old Trafford in September after Pierre-Emerick Aubameyang cancelled out Scott McTominay’s opener.
Both will be eager to get 2020 off to a good start and talkSPORT will be on hand to see who can do so.