Spurs must overturn their 1-0 deficit to make it to the final with the winners of the tie facing Premier League side Liverpool following their heroic victory over Barcelona.
And Spurs boss Mauricio Pochettino has recalled Vertonghen to the line-up following his horror injury in the first leg, while playing Wanyama in midfield alongside Moussa Sissoko. Eric Dier is on the bench.
Forward Heung-min Son is also in the starting XI after being suspended for the first leg in London. There’s no place in the squad for Harry Kane despite whispers he was in contention.
As for Ajax, they make just the one change from the first leg which sees Morocco defender Noussair Mazraoui start in place of Joel Veltman, who’s on the bench.
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