The first Paris derby of the Top 14 season takes place on Sunday when Stade Francais hosts Racing 92 at the Stade Jean-Bouin.
Elsewhere, Toulouse and Castres go head-to-head looking to build on their decent starts to the campaign, while Clermont Auvergne and Toulon face-off in Saturday’s late game at the Marcel Michelin.
Saturday
Toulouse vs Castres
Agen vs Pau
Bordeaux-Bègles vs La Rochelle
Lyon vs Grenoble
Perpignan vs Montpellier
Clermont Auvergne vs Toulon
Sunday
Stade Francais vs Racing 92
Toulouse vs Castres
Stade Ernest-Wallon
One of the matches of the weekend opens the action on Saturday as two potential play-off challengers take on each other at the Stade Ernest-Wallon.
Toulouse were unbeaten heading into Round Five before they were thrashed by Montpellier last Sunday. Ugo Mola fielded a weakened team, however, instead targeting this game against the defending champions.
Castres reside just below Les Rouge et Noir in the table but their tough start to the season continues on Saturday. The fixtures have been unkind to Christophe Urios’ outfit at the beginning of this campaign, but they have managed it superbly and will look forward to home comforts following this encounter.
Last season’s result: Castres won 41-31
Kick-off: 15:10 local (14:10 BST, 13:10 GMT)
Referee: Romain Poite
Assistant referees: Ludovic Cayre, Bruno Gabaldon
TMO: Eric Gonthier
Agen vs Pau
Stade Armandie
Another home match, another game Agen will target following successes against Perpignan and Bordeaux-Bègles when they face Pau.
Philippe Sella’s men, tipped to struggle at the start of the season, have started well at the Stade Armandie and this weekend’s visitors reside just above them in the table.
Simon Mannix’s charges have also lost three of their first five matches and were disappointing against Stade Francais last Sunday, going down 25-13 to the Parisians.
It should be a close contest but at home Agen have shown that they can once again compete against the rest of the division.
Last season’s result: Pau won 20-14
Kick-off: 18:00 local (17:00 BST, 16:00 GMT)
Referee: Laurent Cardona
Assistant referees: Nicolas Datas, Laurent Breil
TMO: Patrick Dellac
Bordeaux-Bègles vs La Rochelle
Matmut Atlantique
Bordeaux may have endured an inauspicious opening four rounds but they found their form to end Clermont Auvergne’s unbeaten start to the campaign.
UBB will look to build on that performance and result against La Rochelle, who themselves produced their best display of the season last weekend. They defeated Lyon 30-13 to secure their second successive victory, leaving them just one point behind third place Racing 92.
A loss for the visitors, however, will see them drop behind Bordeaux. That would duly provide Rory Teague, who is under pressure to succeed following the previous year’s failings, with a huge fillip.
The UBB owners have invested heavily in the squad ahead of 2018/19 and a top-six challenge is therefore a pre-requisite for the side.
Last season’s result: Bordeaux won 29-19
Kick-off: 18:00 local (17:00 BST, 16:00 GMT)
Referee: Maxime Chalon
Assistant referees: Laurent Millotte, Eric Soulan
TMO: Philippe Bonhoure
Lyon vs Grenoble
Matmut Stadium de Gerland
After the disappointment of going down to La Rochelle, this game should be much more to Lyon’s liking, with Grenoble struggling in 13th place in the Top 14.
To the newly-promoted side’s credit, they ended their losing streak by overcoming last season’s Pro D2 winners Perpignan in Round Five.
That will no doubt increase confidence but this is an altogether different challenge and one where they will likely falter. Pierre Mignoni’s charges may have only won two matches so far, but a victory here should propel them back into the top-six.
Last season’s result: Did not play
Kick-off: 18:00 local (17:00 BST, 16:00 GMT)
Referee: Pascal Gauzere
Assistant referees: Julien Castaignede, Arnaud Blondel
TMO: Sebastien Minery
Perpignan vs Montpellier
Stade Aime Giral
Perpignan’s time back in France’s top-tier has been a bit of a disaster so far having lost their opening five matches.
They suffered a blow by going down to Grenoble last weekend and also failed to claim a losing bonus-point following the 31-22 defeat.
Christian Lanta’s men have improved since their opening round thrashing at the hands of Stade Francais, but the Stade Aime Giral is not quite the intimidating proposition it used to be.
Montpellier found their form by putting over 60 points on Toulouse and will look to continue that form on Saturday evening.
Last season’s result: Did not play
Kick-off: 18:00 local (17:00 BST, 16:00 GMT)
Referee: Tual Trainini
Assistant referees: Thomas Charabas, Sebastien Hebert
TMO: Denis Grenouillet
Clermont Auvergne vs Toulon
Parc des Sports Marcel Michelin
Saturday’s late match sees two of France’s biggest clubs go head-to-head, but on form this should be a comfortable victory for the hosts.
Toulon still have quality players but they have yet to fire and even the team’s comfortable triumph over Agen suggested that they are nowhere near Clermont at the moment.
Les Jaunards succumbed for the first time this season after losing to Bordeaux but they are still playing well and should have more than enough to defeat Patrice Collazo’s men.
Last season’s result: Clermont won 21-16
Kick-off: 20:45 local (19:45 BST, 18:45 GMT)
Referee: Adrien Descottes
Assistant referees: Cyril Lafon, Jean-Claude Labarbe
TMO: Laurent Sclafer
Stade Francais vs Racing 92
Stade Jean-Bouin
Round Six closes on Sunday with the Paris derby where Stade Francais will look to continue their fine start to the season against their rivals.
Following the issues of the previous campaign, Heyneke Meyer’s men have impressed everyone by their opening to the year.
Four victories in 2018/19 means that they head into the weekend in second position behind Clermont and could end Sunday at the top of the table.
Racing have also started well and reside just below Stade following their impressive triumph over Castres, but they have been slightly inconsistent, with their excellent wins against the defending champions and Toulon being interspersed by poor performances versus Clermont and Toulouse.
Last season’s result: Stade Francais won 27-17
Kick-off: 16:50 local (15:50 BST, 14:50 GMT)
Referee: Alexandre Ruiz
Assistant referees: Pierre Brousset, Patrick Pechambert
TMO: Eric Briquet-Campin