Bayern humiliated Spurs in October, thumping them 7-2 in north London.
Now Mauricio Pochettino has gone and his replacement Jose Mourinho will be looking to exact some sort of revenge for that hammering.
Both sides have already progress from Group B but Tottenham will want to continue the momentum building under Mourinho with a big display in Bavaria.
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Spurs thrashed Burnley 5-0 over the weekend while Bayern lost at Borussia Monchengladbach.